Gene therapy gets hairy

Therapy that gets inside your head--literally.

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Gene expression profiles of giant hairy naevi.

BACKGROUND Congenital neomelanocytic naevi appear in nearly 1% of newborns. Giant hairy naevi (GHN) are uncommon lesions covering large areas of the body. They are of concern because they have the potential to transform into malignant melanomas. AIMS To describe gene expression profiles of GHN and nearby normal skin from patients with GHN and normal control skin (from patients with cleft lip/...

ژن درمانی Gene Therapy

Fly gene discovery gets at root of branching structures.

BRAF inhibitor: targeted therapy in hairy cell leukemia.

In this issue of Blood, Dietrich et al report that the low-dose BRAF inhibitor, vemurafenib, is highly effective in refractory hairy cell leukemia. Despite enormous progress that has been made with purine nucleoside analogs as the initial treatment of patients with hairy cell leukemia, the relapse rate and eventual development of refractory disease mandate the continued search for effective new...